Preeclampsia Diagnosis and Detection Using the Urinary Markers – Research Proposal Example

The paper “Preeclampsia Diagnosis and Detection Using the Urinary Markers" is a fascinating example of a research proposal on health sciences & medicine. During the pregnancy period, it is important to determine the blood pressure level for women. In this practice, it has been found that over a tenth of the pregnant women record higher blood pressure than the normal level. Preeclampsia is the most common form of hypertensive disorder during pregnancy that is found to affect 5% of the first time mothers. The research will analyze patients who are confirmed for preeclampsia measure, the difference existing between a normal pregnancy and Preeclampsia and the significance of the test (Carty, 2012).
Justification
It is important to consider the diagnosis and detection for early management and treatment as it is cited as a major cause of fetal and maternal morbidity as well as mortality worldwide. Only a few studies have been able to analyze the process of diagnosis and detection of preeclampsia. Even though there are different tests that can be carried out for early detection, little knowledge is known about the impact and strength of urinary markers. Podocyturia is highly specific and a sensitive marker for the preeclampsia among pregnant women. (Chaiworapongsa et al.,2002).
Objective
The research will recognize the weaknesses and strengths of Urinary markers and how they can be used in the diagnosis and detection of hypertensive. This research will also identify the importance of early pregnancy, urinary markers that would assist in identifying whether a woman is destined in developing Preeclampsia disorder (Chaiworapongsa et al., 2002).
Research Question
1. What is the significance of podocyturia urine markers for women diagnosed with preeclampsia?
2. What are the differences between a pregnancy in a normal woman and one who has Preeclampsia?
Literature Review
Preeclampsia is considered a pregnancy-specific disorder in women. It is one of the major causes of mortality, morbidity among maternal and prenatal. Understanding the significance of urine marker test, and differences between a normal woman and Preeclampsia would assist health care professionals in saving a life for the mother and the unborn (Manjareeka & Nanda, 2013). Preeclampsia complications occur in 2-8% of all pregnancies across the world that result in over 63,000 maternal deaths annually. The rate in maternal death is higher in developing countries as compared to developed countries.
However, the condition is a life-threatening occurrence even in the developed world (Saritas & Moeller, 2014). The complications that are linked with the condition include eclampsia, abruption, cerebral hemorrhage, edema in the pulmonary, hepatic failure, Haemolysis Elevated Liver enzymes, Low Platelet count and also acute renal failure (Dekker & Sibai, 1991). It is also a major cause of prenatal deaths among the unborn. It is found that women who had an earlier experience of Preeclampsia complications are likely to experience cardiac attack, cerebrovascular, peripheral arterial diseases and also higher cardiovascular mortality. Previous pregnancy with the condition is found to be the major risk factor though it is believed that Preeclampsia has multivariate risk factors (Bolte, van Geijn & Dekker, 2001).  Methodology
Population of Study
The study population will involve healthy women as well as women with Preeclampsia complications who were in their 20 weeks and 38 weeks of pregnancy. The study targeted women with singleton pregnancy for the research. The study will not include women with a concurrent diagnosis of the diseases that affect their blood pressure, such as chronic hypertension prior to pregnancy. Urine samples were collected from these women to determine the changes they experienced during the period (Seini, 2013).
Ethics of Research
The research required approval from the ethics committee in the health center due to human involvement throughout the study. Through this, the women to be involved in this research will be at their will where they will be expected to sign the consent forms (Karacay et al., 2010).
Statistical Analysis of Data
The data and statistics collected will be evaluated using the software called SPSS. It is a statistical tool that determines the trends and comparison in a wide variety of data.
The implication of this Study
The study findings will be crucial in understanding the significance of urine marker test in the diagnosis of preeclampsia. The suggestions in the recommendation section will be crucial in advising patients and medical practitioners in the field of preeclampsia detection, diagnosis and treatment using the Urine marker (Kolialexi, et al., 2015).