Success of Aspirin Regimens and Lifestyle Changes – Research Proposal Example
NURSING EVIDENCE Objective of the Study The purpose of this research is to determine how lifestyle modification compared to Aspirin Regimen reduces the risk of a Heart Attack during a 2-3 year long-term treatment. This research involves assessing the comparative effectiveness of Aspirin regimens versus lifestyle modifications.
Eligibility Criteria: This study will involve the meta-analyses of specific randomized controlled trials comparing the success of Aspirin regimens and lifestyle changes.
Data Sources: The Cochrane and Medline Database of Systematic Reviews.
Brief Overview of the Study
The researchers will carry out a comprehensive assessment of already published meta-analyses on themes with randomized trial data on both Aspirin regimens as well as lifestyle changes. For both these conditions, the researchers will combine the available data from multiple network meta-analyses to evaluate the statistics in the existing evidence, and to decide on the comparative effectiveness of lifestyle interventions and Aspirin regimens in decreasing women’s risk of heart attack.
Heart attack is one of the main leading causes of death in the elderly women between the ages of 45-75 years. Research shows that both lifestyle modification and daily Aspirin therapy can help reduce the risk of heart attack (Aadahl, Toft & Toft, 2011). However, it is important to note that aspirin regime is not right for everyone. It should only be used when prescribed a physician. Patients with a serious history of bleeding and allergy cannot be prescribed to this dosage. The proposed solution is to use lifestyle modification as the most effective remedy to heart diseases. Lifestyle modification can be used by just anyone and can come in many forms which are comfortable to anyone. One can change his or hear eating habits and opt healthy eating, one can also exercise regularly and so on. This was the expected solution. Advising the patients and the general public as well is the most effective way to curbing the risks of heart attacks as it has no side effects and other complications at all. It is the most realistic intervention since it is less costly and there is readily available training to deliver this intervention (Crouch, Wilson & Newbury, 2011).
The organization culture incorporates the meanings, values, norms, beliefs, habits and symbols that people attach to behaviors. In this context, lifestyle modification is a behavior that is well known to the society but little is done on this. Many people opt for unhealthy eating habits and rarely exercise. In America for example, cardio-vascular diseases are the highest cause of death and are as a result of unhealthy lifestyle. This can be controlled through the modification of lifestyle (Hales, 2009).
The expected outcomes of this project are that lifestyle modification is basically better compared to aspirin regime when it comes to reducing the risk of heart diseases in elderly women. This is because unlike lifestyle modification which has no side effects, aspirin regime has a number of side effects which can be very hazardous to the health. To some extent, aspirin therapy can reduce this risk but will have eventual side effects since it affects blood clotting and can lead to internal bleeding.
Methods to Achieve outcomes
From every eligible trial, the researchers will extract the participants’ numbers, the respondents who experienced heart attacks in every trial arm, and the publication year. There will be different researchers who are entrusted with the procedures of extracting information, and ensuring that all the gathered data is accurate (Schou, Jensen, Zwisler & Wagner, 2008).
From this outcome, there is a significant impact on several indicators. The quality of improvement will increase since all involved parties will be aware of the importance of lifestyle modification. The patient-centered quality care will improve as well as result of this new awareness. Environmental changes will be considered as it is a form of lifestyle modification which can lower the risk of heart attack. Finally, professional expertise will also improve as the doctors will be in a position to advise the patients with viable research results (Lee, 2005).
Due to the fact that new trials are always being conducted on the effectiveness of lifestyle changes and Aspirin regimens on decreasing the incidence of heart attacks among middle-ages women, it is likely that a number of the meta-analyses may be outdated. This means that this research could underestimate the scale of available information on the effects of lifestyle changes as well as Aspirin regimens.
Aadahl, M. L., Toft, U., Pisinger, C., & Jørgensen, T. (2011). Does a population-based multifactorial lifestyle intervention increase social inequality in physical activity? The Inter 99 study. British Journal of Sports Medicine, 45(3), 209-215.
American Heart Association. (2012). Aspirin and Heart Disease. http://www.heart.org/HEARTORG/Conditions/HeartAttack/PreventionTreatmentofHeartAttack/Aspirin-and-Heart-Disease_UCM_321714_Article.jspDec 11,2012
American Heart Association. (2013). What is Cardiovascular Disease (Heart Disease)? Retrieved September 25, 2014 from http://www.heart.org/HEARTORG/Caregiver/Resources/WhatisCardiovascularDisease/
Berger, J. S., Roncaglioni, M. C., Avanzini, F., Pangrazzi, I., Tognoni, G., & Brown, D. L. (2006). Aspirin for the primary prevention of cardiovascular events in women and men. JAMA, 295, 306-313.
Bulugahapitiya, U., Siyambalapitiya, S., Sithole, J., Fernando, D. J., & Idris, I. (2008). Age threshold for vascular prophylaxis by aspirin in patients without diabetes. Heart, 94, 1429-1432.
Crouch, R., Wilson, A., & Newbury, J. (2011). A systematic review of the effectiveness of primary health education or intervention programs in improving rural womens knowledge of heart disease risk factors and changing lifestyle behaviours. International Journal of Evidence-Based Healthcare, 9(3), 236-245.
Elwood, P., Morgan, G., Brown, G., & Pickering, J. (2005). Aspirin for everyone older than 50? For. BMJ, 330, 1440-1441
Galbraith, E. M., Mehta, P. K., Veledar, E., Vaccarino, V., & Wenger, N. K. (2011). Women and Heart Disease: Knowledge, Worry, and Motivation. Journal Of Womens Health (15409996), 20(10), 1529-1534.
Graffagnino, C. L., Falko, J. M., La Londe, M., Schaumburg, J., Hyek, M. F., & Shaffer, L. E. T. (2006). Effect of a community-based weight management program on weight loss and cardiovascular disease risk factors. Obesity, 14(2), 280–288.
Greving, J. P., Buskens, E., Koffijberg, H., & Algra, A. (2008). Cost-effectiveness of aspirin in the primary prevention of cardiovascular disease in subgroups based on age, gender, and varying cardiovascular risk. Circulation, 117, 2875-2883.
Hales, D. R. (2009). An invitation to health. Australia: Wadsworth Cengage Learning. National Institute of Health (2013) Medline Plus: Heart Disease in Women Retrieved September 27, 2014 from http://www.nlm.nih.gov/medlineplus/heartdiseaseinwomen.html
Harvard Heart . (2014). Daily low-dose aspirin can prevent heart attack and stroke but is often misused. Retrieved fromhttp://www.health.harvard.edu/press_releases/daily-low-dose-aspirin-can-prevent-heart-attack-and-stroke-but-is-often-misused
Lee, P., Chen, W., & Ng, W. (2005). Low-dose aspirin increases aspirin resistance in patients with coronary artery disease. Am J Med, 118, 723-727.
Nelson, M. R., Liew, D., & Bertram, M. (2005). Epidemiological modelling or routine use of low dose aspirin for the primary prevention of coronary heart disease and stroke in those aged _ 70. BMJ, 330, 1306- 1311.
Ridker, P. M., Cook, N. R., & Lee, I. M. (2005). A randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease in women. N Engl J Med., 352, 1293-1304.
Schou, L., Jensen, B., Zwisler, A., & Wagner, L. (2008). Womens experiences with cardiac rehabilitation-- participation and non-participation. Nordic Journal Of Nursing Research & Clinical Studies / Vård I Norden, 28(4), 24-28.
The New York Times. (2012). Physical Activity: Exercises Effects on the Heart. Retrieved September 28, 2014 from http://health.nytimes.com/health/guides/specialtopic/physical-activity/exercises-effects-on-the-heart.html
Villareal, D. T., Miller, B. V. III., Banks, M., Fontana, L., Sinacore, D. R., & Klein, S. (2006). Effect of lifestyle intervention on metabolic coronary heart disease risk factors in obese older adults. Am J Clin Nutr., 84(6), 1317–1323.
Wister, A. P., Loewen, N. M. D., Kennedy-Symonds, H. M., McGowan, B. M. D., McCoy, B. M. A., & Singer, J. P. (2007). One-year follow-up of a therapeutic lifestyle intervention targeting cardiovascular disease risk. CMAJ., 177(8), 859–865.
Wolff, T., Miller, T., & Ko, S. (2009). U.S. Preventive Services Task Force: Aspirin for the Primary Prevention of Cardiovascular Events. Retrieved from http://www.uspreventiveservicestaskforce.org/uspstf09/aspirincvd/aspcvdart.htm