Hutchinson Gilford Progeria Syndrome – Research Paper Example
The paper "Hutchinson Gilford Progeria Syndrome" is an outstanding example of a biology research paper.
Hutchinson Gilford Progeria Syndrome is a congenital disorder which is responsible for early aging which starts as soon as 1 year. It has a reference number 176670. The laminin A gene that is the LMNA is affected in this syndrome. When the gene is mapped it is observed at 1q21.2. It has been suggested that this disease follows an autosomal dominant pattern but in the case of siblings, it has an autosomal recessive pattern. It has also been discovered that this disease is mainly transmitted from the mother. The allelic frequency for the condition is 0.05.
The most prominent symptom of progeria is early aging which starts as early as one year. There is a cessation of growth at a very early age which can be as low as 3 years. The affected child has a short stature and can suffer from mental retardation. The height of the affected children is small and their stature is similar to that of old people. They have loss of hair and their skin appears to be similar to those of old people as well. They have cardiovascular effects which are the main cause for the death of the patients. These patients cannot survive for a very long time and die at the age of 13.
This disease is a very rare condition and children suffering from it may suffer strokes at an early age of 5 or 6 years. They have complications in operations as well because their skin loses its elasticity and it is almost impossible for the wound to heal.
Question 1: Is it possible to cure children who are suffering from this condition?
Question 2: Do racial and environmental factors play a role in causing this syndrome?
Question 3: Can this syndrome be diagnosed when the fetus is in the uterus?
Question 4: Is progeria more common in males than in females?
Question 5: Progeria is a condition which causes premature aging basically. Then why is it associated with mental retardation?