T Cell and B Cell – Assignment Example
The paper "T Cell and B Cell" is a wonderful example of a biology assignment. The T cell has various relations and interconnections in the transfer and trigger of various responses. The CD4+ tends to trigger the generation of the CD8+ T lymphocytes. B cells differ from T cells through the activation, division, and acquisition of the effector functions and generation of the memory. The T cells bear identical cell receptors with heterogeneous differentiation processes involving clonal expansion. The physiological compartments of the lymph nodes and the blood are connected and hence control the dynamics of the immune cells. The CD4 and CD8 T cells have similarities and differences. The difference between them is that the CD4T cells display restrictive proliferation while CD8 T cell undergoes extensive proliferation while responding to infections. Finally, the memory cells can be maintained for the long-term through the CD4+ T cell. The generation of B cell memory requires the help of the CD4+ cell, and it involves the triggering of CD40 in the target B cells. The same signals are also relevant in the generation of the memory CD8+ T lymphocytes. In contrast to B cells, T cell is relevant in activation, acquisition, and division of the effector functions and memory generation. All these are integrated parts of the same developmental program because they are interconnected and sequential events (Chulwoo 1). According to studies, native T cells bearing identical T cell receptors tend to experience heterogeneous differentiation and processes of clonal expansion. The controllers of this outcome are not well characterized and their contributions to the dynamics of cell immunity that is poorly understood. There is a connection between the physiological compartments of blood and lymph nodes determine how to control the dynamics of the immune cells. The multi-organ model integrates tissue and cellular level events thus allowing for the examination of the heterogeneous differentiation of the individual precursor native T cells into generating memory T lymphocytes and effector. The proliferation and differentiation of the Ag-specific CD4 and CD8 T cells can be identified through Listeria infection. When responding to an infection, the CD4 divides into a limited number of times with progeny that exhibits proliferative arrests in early divisions. The CD4 T cells display this restricted proliferative patterns and are not driven to into extensive clonal expansion. However, CD8 T cells undergo extensive proliferation in response to infection. Memory cells can be maintained by different mechanisms. It is proven that CD4+ T cell plays a major role in generating the CD8+ T cell-mediated from the secondary challenge. Both of the cells are required for the long-term maintenance of the CD8+ memory T cells in responding to interleukin-7.