Guillain-Barr Syndrome in the Pediatric Population - Article Example

Background information that Guillain-Barre syndrome is a significant factor in the occurrence of neuromuscular paralysis and the possible association between Campylobacter jejuni and BSC informed the study. The authors sought to investigate the incidence of Campylobacter jejuni among children with Guillain-Barre syndrome and factors to the association between the GBS and Campylobacter jejuni and used a case study design, with a controlled set up, in implementing the study. A sample of 47 children from Tabriz children’s hospital and having GBS complications in a two-year period, beginning from July 2006 and 33 healthy children, were used in the study that also investigated the occurrence of Campylobacter jejuni in the participants.

Results showed a significant difference between the association between GBS and Campylobacter in the admitted patients (40.4 percent) and the association in the participants outside the hospital set up (6.1 percent, p= 0.001). Participants with Campylobacter jejuni also took significantly longer duration to walk independently than those without the complication did (p= 0.013). Most of the patients with Campylobacter jejuni were, however, able to walk independently within a year. These patients were also at a greater risk of suffering from axonal neuropathy.

The authors conclude that Campylobacter jejuni preceded GBS (Barzegar, Hashemilar, and Bonyadi, 2010). Applied design, the large sample size, professional approach to data collection, level of the study (being level 3), and longitudinal approach to the study establish validity and reliability for generalization (Barzegar, Hashemilar, and Bonyadi, 2010).